{"id":7215,"date":"2012-06-10T21:44:55","date_gmt":"2012-06-10T20:44:55","guid":{"rendered":"http:\/\/www.ilmelanoma.com\/?p=7215"},"modified":"2026-10-16T10:44:39","modified_gmt":"2026-10-16T09:44:39","slug":"dabrafenib-a-new-melanoma-drug-in-metastatic-melanoma","status":"publish","type":"post","link":"https:\/\/www.ilmelanoma.com\/en\/dabrafenib-a-new-melanoma-drug-in-metastatic-melanoma\/","title":{"rendered":"Dabrafenib a new melanoma drug in metastatic melanoma"},"content":{"rendered":"<p>The BRAF inhibitor dabrafenib shows promising results for treatment of advanced\u00a0melanoma, both alone and in combination with the MEK inhibitor trametinib, show results from two studies presented at the American Society of Clinical\u00a0Oncology\u00a0Annual Meeting in Chicago, Illinois, USA.\u00a0The BREAK-3 study compared treatment with dabrafenib with that of standard dacarbazine\u00a0chemotherapy\u00a0for patients with previously untreated, advanced melanoma and mutations in the\u00a0<em>BRAF<\/em>\u00a0gene.\u00a0The researchers found that the risk for disease progression was reduced by a significant 70% in the dabrafenib group versus the dacarbazine group.<\/p>\n<p><a href=\"https:\/\/www.news-medical.net\/news\/20120608\/Promising-results-for-dabrafenib-in-advanced-melanoma.aspx\" target=\"_blank\">Read more in medical news<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The BRAF inhibitor dabrafenib shows promising results for treatment of advanced\u00a0melanoma, both alone and in combination with the MEK inhibitor trametinib, show results from two studies presented at the American Society of Clinical\u00a0Oncology\u00a0Annual Meeting in Chicago, Illinois, USA.\u00a0The BREAK-3 study compared treatment with dabrafenib with that of standard dacarbazine\u00a0chemotherapy\u00a0for patients with previously untreated, advanced melanoma [&hellip;]<\/p>\n","protected":false},"author":13,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-7215","post","type-post","status-publish","format-standard","hentry","category-cura-melanoma"],"_links":{"self":[{"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/posts\/7215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/comments?post=7215"}],"version-history":[{"count":1,"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/posts\/7215\/revisions"}],"predecessor-version":[{"id":10780,"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/posts\/7215\/revisions\/10780"}],"wp:attachment":[{"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/media?parent=7215"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/categories?post=7215"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ilmelanoma.com\/en\/wp-json\/wp\/v2\/tags?post=7215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}