The ABCDE rule (Asymmetry, Border irregularity, Color variegation, Diameter >6 mm, elevation or evolution), originally described by Friedman et al., is a useful tool in facilitating the diagnosis of malignant melanoma and it is now included among The Seven Warning Signals of Cancer of “The American Cancer Society” and it’s a simple method that can identify nevi at risk. The ABCDE is a simple method that can help describe a subset of melanomas, namely early, thin tumorsthat might otherwise be confused with benign pigmented lesions.
- ABCDE : Irregular border
- Irregular border: A mole with birregular edges.